{"id":15401,"date":"2013-08-29T10:30:42","date_gmt":"2013-08-29T14:30:42","guid":{"rendered":"http:\/\/therapytoronto.ca\/news\/?p=15401"},"modified":"2013-08-30T10:34:18","modified_gmt":"2013-08-30T14:34:18","slug":"neuroscientists-find-a-key-to-reducing-forgetting-its-about-the-network","status":"publish","type":"post","link":"https:\/\/therapytoronto.ca\/news\/2013\/08\/neuroscientists-find-a-key-to-reducing-forgetting-its-about-the-network\/","title":{"rendered":"Neuroscientists find a key to reducing forgetting &#8212; it&#8217;s about the network"},"content":{"rendered":"<p>From the New York University media release:<\/p>\n<blockquote><p><a href=\"http:\/\/therapytoronto.ca\/news\/wp-content\/uploads\/2013\/06\/memory-neurons.jpg\"><img loading=\"lazy\" class=\"alignright size-full wp-image-14281\" alt=\"memory neurons\" src=\"http:\/\/therapytoronto.ca\/news\/wp-content\/uploads\/2013\/06\/memory-neurons.jpg\" width=\"270\" height=\"251\" \/><\/a>A team of neuroscientists has found a key to the reduction of forgetting. Their findings, which appear in the journal\u00a0<i>Neuron<\/i>, show that <strong>the better the coordination between two regions of the brain, the less likely we are to forget newly obtained information<\/strong>.<\/p>\n<p>The study was conducted at New York University by Lila Davachi, an associate professor in NYU&#8217;s Department of Psychology and Center for Neural Science, and Kaia Vilberg, now a postdoctoral researcher at the University of Texas&#8217; Center for Vital Longevity and School of Behavioral and Brain Sciences in Dallas.<\/p>\n<p>&#8220;<strong>When memories are supported by greater coordination between different parts of the brain, it&#8217;s a sign that they are going to last longer<\/strong>,&#8221; explained Davachi.<\/p>\n<p>It is commonly understood that the key to memory consolidation\u2014the cementing of an experience or information in our brain\u2014is signaling from the brain&#8217;s hippocampus across different cortical areas. Moreover, <strong>it has been hypothesized, but never proven, that the greater the distribution of signaling, the stronger the memory takes hold in our brain<\/strong>.<\/p>\n<p>In the\u00a0<i>Neuron<\/i>\u00a0study, Davachi and Vilberg sought to determine if there was scientific support for this theory.<\/p>\n<p>To do so, they examined how memories are formed at their earliest stages through a series of experiments over a three-day period.<\/p>\n<p><strong>On day one of the study, the researchers aimed to encode, or create, new memories among the study&#8217;s subjects<\/strong>. Here, they showed participants a series of images\u2014objects and outdoor scenes, both of which were paired with words. Here, subjects were asked to form an association between the word and image presented on the screen.<\/p>\n<p><strong>On day two, the subjects returned to the lab and completed another round of encoding tasks using new sets of visuals and words<\/strong>. This allowed to the researchers to compare two types of memory: the more consolidated, long duration (LD) memories encoded on day one with the less consolidated, short duration (SD) memories encoded on day two.<\/p>\n<p>After a short break, participants were placed in an MRI machine\u2014in order to monitor neural activity\u2014and viewed the same visual-word pairings they saw on days one and two as well as a new round of visuals paired with words. <strong>They then completed a memory test of approximately half of the visual-word pairings they&#8217;d seen thus far<\/strong>. On day three, they returned to the lab for a memory test on the remaining visuals.<\/p>\n<p><strong>By testing over multiple days, the researchers were able to isolate memories that declined or were preserved over time<\/strong> and, with it, better understand the neurological factors that contribute to memory preservation.<\/p>\n<p>Their results showed that <strong>memories (i.e., the visual-word associations) that were not forgotten were associated with greater coordination between the hippocampus and left perirhinal cortex (LPRC)<\/strong>\u2014two parts of the brain previously linked with memory formation. By contrast, there was notably less connectivity between these regions for visual-word associations that the study&#8217;s subjects tended to forget.<\/p>\n<p>Moreover, the researchers found that <strong>the coordinated brain activity between the hippocampus and the LPRC\u2014but not overall activity in these regions\u2014was related to memory strengthening<\/strong>, arguing for the network&#8217;s contribution to memory longevity.<\/p>\n<p>&#8220;These findings show the brain strengthens memories by distributing them across networks,&#8221; explained Davachi. &#8220;However, this process takes time. <strong>Day-old memories show greater coordinated brain activity compared to recent ones<\/strong>. This suggests that coordinated brain activity increases with time after a memory is initially formed.&#8221;<\/p><\/blockquote>\n<p>The research was supported by a grant from the National Institute of Mental Health (RO1\u2013MH074692) and Dart Neuroscience.<\/p>\n<!-- AddThis Advanced Settings generic via filter on the_content --><!-- AddThis Share Buttons generic via filter on the_content -->","protected":false},"excerpt":{"rendered":"<p>From the New York University media release: A team of neuroscientists has found a key to the reduction of forgetting. Their findings, which appear in the journal\u00a0Neuron, show that the&#8230; <a class=\"read-more-link\" href=\"https:\/\/therapytoronto.ca\/news\/2013\/08\/neuroscientists-find-a-key-to-reducing-forgetting-its-about-the-network\/\">Read more &raquo;<\/a><!-- AddThis Advanced Settings generic via filter on get_the_excerpt --><!-- AddThis Share Buttons generic via filter on get_the_excerpt --><\/p>\n","protected":false},"author":5,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[321,4,6],"tags":[],"_links":{"self":[{"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/posts\/15401"}],"collection":[{"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/comments?post=15401"}],"version-history":[{"count":1,"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/posts\/15401\/revisions"}],"predecessor-version":[{"id":15405,"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/posts\/15401\/revisions\/15405"}],"wp:attachment":[{"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/media?parent=15401"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/categories?post=15401"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/tags?post=15401"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}