{"id":16286,"date":"2014-02-03T09:51:11","date_gmt":"2014-02-03T14:51:11","guid":{"rendered":"http:\/\/therapytoronto.ca\/news\/?p=16286"},"modified":"2014-02-03T02:44:41","modified_gmt":"2014-02-03T07:44:41","slug":"study-shows-autistic-brains-create-more-information-at-rest","status":"publish","type":"post","link":"https:\/\/therapytoronto.ca\/news\/2014\/02\/study-shows-autistic-brains-create-more-information-at-rest\/","title":{"rendered":"Study shows autistic brains create more information at rest"},"content":{"rendered":"<p>From the Case Western Reserve University media release:<\/p>\n<blockquote><p><a href=\"http:\/\/therapytoronto.ca\/news\/wp-content\/uploads\/2013\/07\/autism-lonely-child.jpg\"><img loading=\"lazy\" class=\"alignright size-full wp-image-14703\" alt=\"autism lonely child\" src=\"http:\/\/therapytoronto.ca\/news\/wp-content\/uploads\/2013\/07\/autism-lonely-child.jpg\" width=\"290\" height=\"193\" \/><\/a>New research from Case Western Reserve University and University of Toronto neuroscientists finds that <strong>the brains of autistic children generate more information at rest &#8212; a 42% increase on average<\/strong>.<\/p>\n<p>The study offers a scientific explanation for the most typical characteristic of autism &#8212; withdrawal into one&#8217;s own inner world. The <strong>excess production of information may explain a child&#8217;s detachment from their environment<\/strong>.<\/p>\n<p>Published at the end of December in <em>Frontiers in Neuroinformatics<\/em>, this study is a follow-up to the authors&#8217; prior finding that brain connections are different in autistic children. This paper determined that the differences account for the increased complexity within their brains.<\/p>\n<p>&#8220;Our results suggest that <strong>autistic children are not interested in social interactions because their brains generate more information at rest<\/strong>, which we interpret as more introspection in line with early descriptions of the disorder,&#8221; said Roberto Fern\u00e1ndez Gal\u00e1n, PhD, senior author and associate professor of neurosciences at Case Western Reserve School of Medicine.<\/p>\n<p>The authors quantified information as engineers normally do but instead of applying it to signals in electronic devices, they applied it to brain activity recorded with magnetoencephalography (MEG). They showed that autistic children&#8217;s brains at rest generate more information than non-autistic children. This may explain their lack of interest in external stimuli, including interactions with other people.<\/p>\n<p>The researchers also quantified interactions between brain regions, i.e., the brain&#8217;s functional connectivity, and determined the inputs to the brain in the resting state allowing them to interpret the children&#8217;s introspection level.<\/p>\n<p>&#8220;<strong>This is a novel interpretation because it is a different attempt to understand the children&#8217;s cognition by analyzing their brain activity<\/strong>,&#8221; said Jos\u00e9 L. P\u00e9rez Vel\u00e1zquez, PhD, first author and professor of neuroscience at University of Toronto Institute of Medical Science and Department of Pediatrics, Brain and Behavior Center.<\/p>\n<p>&#8220;Measuring cognitive processes is not trivial; yet, our findings indicate that this can be done to some extent with well-established mathematical tools from physics and engineering.&#8221;<\/p>\n<p><strong>This study provides quantitative support for the relatively new &#8220;Intense World Theory&#8221; of autism<\/strong> proposed by neuroscientists Henry and Kamila Markram of the Brain Mind Institute in Switzerland, which describes the disorder as the result of hyper-functioning neural circuitry, leading to a state of over-arousal.<\/p>\n<p>More generally, the work of Gal\u00e1n and P\u00e9rez Vel\u00e1zquez is an initial step in the investigation of how information generation in the brain relates to cognitive\/psychological traits and will begin to frame neurophysiological data into psychological aspects. The team now aims to apply a similar approach to patients with schizophrenia.<\/p><\/blockquote>\n<p>Gal\u00e1n is a scholar of The Mt. Sinai Health Care Foundation and former fellow of The Alfred P. Sloan Foundation.<\/p>\n<!-- AddThis Advanced Settings generic via filter on the_content --><!-- AddThis Share Buttons generic via filter on the_content -->","protected":false},"excerpt":{"rendered":"<p>From the Case Western Reserve University media release: New research from Case Western Reserve University and University of Toronto neuroscientists finds that the brains of autistic children generate more information&#8230; <a class=\"read-more-link\" href=\"https:\/\/therapytoronto.ca\/news\/2014\/02\/study-shows-autistic-brains-create-more-information-at-rest\/\">Read more &raquo;<\/a><!-- AddThis Advanced Settings generic via filter on get_the_excerpt --><!-- AddThis Share Buttons generic via filter on get_the_excerpt --><\/p>\n","protected":false},"author":5,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[331,6,9],"tags":[],"_links":{"self":[{"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/posts\/16286"}],"collection":[{"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/comments?post=16286"}],"version-history":[{"count":1,"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/posts\/16286\/revisions"}],"predecessor-version":[{"id":16290,"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/posts\/16286\/revisions\/16290"}],"wp:attachment":[{"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/media?parent=16286"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/categories?post=16286"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/tags?post=16286"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}