{"id":16669,"date":"2014-04-24T09:57:23","date_gmt":"2014-04-24T13:57:23","guid":{"rendered":"http:\/\/therapytoronto.ca\/news\/?p=16669"},"modified":"2014-04-26T10:24:27","modified_gmt":"2014-04-26T14:24:27","slug":"sleep-disorder-linked-to-brain-disease","status":"publish","type":"post","link":"https:\/\/therapytoronto.ca\/news\/2014\/04\/sleep-disorder-linked-to-brain-disease\/","title":{"rendered":"Sleep disorder linked to brain disease"},"content":{"rendered":"<p>From the University of Toronto media release:<\/p>\n<blockquote><p><a href=\"http:\/\/therapytoronto.ca\/news\/wp-content\/uploads\/2013\/01\/sleeping_older_couple.jpg\"><img loading=\"lazy\" class=\"alignright size-full wp-image-9619\" alt=\"sleeping older couple\" src=\"http:\/\/therapytoronto.ca\/news\/wp-content\/uploads\/2013\/01\/sleeping_older_couple.jpg\" width=\"300\" height=\"200\" \/><\/a>Researchers at the University of Toronto say a sleep disorder that causes people to act out their dreams is the best current predictor of brain diseases like Parkinson&#8217;s and Alzheimer&#8217;s.<\/p>\n<p>&#8220;<strong>Rapid-eye-movement sleep behaviour disorder (RBD) is not just a precursor but also a critical warning sign of neurodegeneration that can lead to brain disease<\/strong>,&#8221; says associate professor and lead author Dr. John Peever. In fact, as many as 80 to 90 per cent of people with RBD will develop a brain disease.&#8221;<\/p>\n<p>As the name suggests, <strong>the disturbance occurs during the rapid-eye-movement (REM) stage of sleep and causes people to act out their dreams<\/strong>, often resulting in injury to themselves and\/or bed partner. In healthy brains, muscles are temporarily paralyzed during sleep to prevent this from happening.<\/p>\n<p>&#8220;<strong>It&#8217;s important for clinicians to recognize RBD as a potential indication of brain disease in order to diagnose patients at an earlier stage<\/strong>,&#8221; says Peever. &#8220;This is important because drugs that reduce neurodegeneration could be used in RBD patients to prevent (or protect) them from developing more severe degenerative disorders.&#8221;<\/p>\n<p>His research examines the idea that <strong>neurodegeneration might first affect areas of the brain that control sleep before attacking brain areas that cause more common brain diseases like Alzheimer&#8217;s<\/strong>.<\/p>\n<p>Peever says he hopes the results of his study lead to earlier and more effective treatment of neurodegenerative diseases.<\/p><\/blockquote>\n<p>Professor John Peever is an associate professor in U of T&#8217;s Department of Cell and Systems Biology. His research is available in print and online in the latest issue of Trends in Neuroscience.<\/p>\n<!-- AddThis Advanced Settings generic via filter on the_content --><!-- AddThis Share Buttons generic via filter on the_content -->","protected":false},"excerpt":{"rendered":"<p>From the University of Toronto media release: Researchers at the University of Toronto say a sleep disorder that causes people to act out their dreams is the best current predictor&#8230; <a class=\"read-more-link\" href=\"https:\/\/therapytoronto.ca\/news\/2014\/04\/sleep-disorder-linked-to-brain-disease\/\">Read more &raquo;<\/a><!-- AddThis Advanced Settings generic via filter on get_the_excerpt --><!-- AddThis Share Buttons generic via filter on get_the_excerpt --><\/p>\n","protected":false},"author":5,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[321,10,43],"tags":[],"_links":{"self":[{"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/posts\/16669"}],"collection":[{"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/comments?post=16669"}],"version-history":[{"count":1,"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/posts\/16669\/revisions"}],"predecessor-version":[{"id":16675,"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/posts\/16669\/revisions\/16675"}],"wp:attachment":[{"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/media?parent=16669"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/categories?post=16669"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/tags?post=16669"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}