{"id":18461,"date":"2015-11-02T15:56:25","date_gmt":"2015-11-02T20:56:25","guid":{"rendered":"http:\/\/therapytoronto.ca\/news\/?p=18461"},"modified":"2015-11-02T15:56:25","modified_gmt":"2015-11-02T20:56:25","slug":"lack-of-sleep-may-zap-cell-growth-brain-activity-study-in-plants-suggests","status":"publish","type":"post","link":"https:\/\/therapytoronto.ca\/news\/2015\/11\/lack-of-sleep-may-zap-cell-growth-brain-activity-study-in-plants-suggests\/","title":{"rendered":"Lack of &#8216;sleep&#8217; may zap cell growth, brain activity, study in plants suggests"},"content":{"rendered":"<p>From the University of Tennessee at Knoxville\u00a0media release:<\/p>\n<blockquote>\n<p id=\"first\" class=\"lead\"><a href=\"http:\/\/therapytoronto.ca\/news\/wp-content\/uploads\/2013\/07\/sleep-deprivation.jpg\"><img loading=\"lazy\" class=\"alignright size-full wp-image-14815\" src=\"http:\/\/therapytoronto.ca\/news\/wp-content\/uploads\/2013\/07\/sleep-deprivation.jpg\" alt=\"sleep deprivation\" width=\"290\" height=\"192\" \/><\/a>Lack of adequate sleep can do more than just make you tired. <strong>It can short-circuit your system and interfere with a fundamental cellular process that drives physical growth, physiological adaptation and even brain activity<\/strong>, according to a new study from the University of Tennessee, Knoxville.<\/p>\n<div id=\"text\">\n<p>Albrecht von Arnim, a molecular biologist based in the Department of Biochemistry and Cellular and Molecular Biology, <strong>studied plants but said the concepts may well translate to humans<\/strong>.<\/p>\n<p>His team examined how protein synthesis&#8211;the process that determines how organisms grow and how cells renew themselves&#8211;changes over the course of the daily day-night cycle. He also explored whether any such changes are controlled by the organism&#8217;s internal time keeper, the circadian clock.<\/p>\n<p><strong>Proteins are newly created in every cell by translating messages made from the cell&#8217;s own DNA, the genome<\/strong>.<\/p>\n<p>Von Arnim&#8217;s findings, published in the journal <em>Plant Cell<\/em>, show not only that protein synthesis activity changed over the course of the day, but also that it was under the influence of the circadian clock.<\/p>\n<p>&#8220;When we misalign our behavior with our circadian clock, for example by creating jet lag, or by working as a night owl, <strong>we do not only disrupt normal physiological processes such as cycles of appetite and body temperature<\/strong>,&#8221; von Arnim said. &#8220;This work in plants suggests that we may also be interfering with a more fundamental cellular process, protein synthesis.&#8221;<\/p>\n<p><strong>Muscle action, brain activity, growth and development are functions all performed by proteins whose synthesis is carefully regulated<\/strong>, he said. &#8220;For example, when cells are stressed by high temperatures or from a virus infection, they drastically reduce their protein synthesis activity,&#8221; von Arnim said.<\/p>\n<p><strong>The findings could also have implications for agricultural production<\/strong> as farmers and companies seek to better cultivate land and maximize outputs from plants required to sustain human life.<\/p>\n<p>&#8220;Protein synthesis is part of the basis for crop yield,&#8221; von Arnim said.<\/p>\n<\/div>\n<\/blockquote>\n<!-- AddThis Advanced Settings generic via filter on the_content --><!-- AddThis Share Buttons generic via filter on the_content -->","protected":false},"excerpt":{"rendered":"<p>From the University of Tennessee at Knoxville\u00a0media release: Lack of adequate sleep can do more than just make you tired. It can short-circuit your system and interfere with a fundamental&#8230; <a class=\"read-more-link\" href=\"https:\/\/therapytoronto.ca\/news\/2015\/11\/lack-of-sleep-may-zap-cell-growth-brain-activity-study-in-plants-suggests\/\">Read more &raquo;<\/a><!-- AddThis Advanced Settings generic via filter on get_the_excerpt --><!-- AddThis Share Buttons generic via filter on get_the_excerpt --><\/p>\n","protected":false},"author":5,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[339,43],"tags":[],"_links":{"self":[{"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/posts\/18461"}],"collection":[{"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/comments?post=18461"}],"version-history":[{"count":1,"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/posts\/18461\/revisions"}],"predecessor-version":[{"id":18467,"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/posts\/18461\/revisions\/18467"}],"wp:attachment":[{"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/media?parent=18461"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/categories?post=18461"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/tags?post=18461"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}