{"id":18659,"date":"2016-01-06T01:13:52","date_gmt":"2016-01-06T06:13:52","guid":{"rendered":"http:\/\/therapytoronto.ca\/news\/?p=18659"},"modified":"2016-01-06T01:13:52","modified_gmt":"2016-01-06T06:13:52","slug":"inflammation-can-fan-the-flames-of-depression","status":"publish","type":"post","link":"https:\/\/therapytoronto.ca\/news\/2016\/01\/inflammation-can-fan-the-flames-of-depression\/","title":{"rendered":"Inflammation can fan the flames of depression"},"content":{"rendered":"<p>From the Rice University media release:<\/p>\n<blockquote><p><strong><a href=\"http:\/\/therapytoronto.ca\/news\/wp-content\/uploads\/2013\/02\/depressed_bullied_worker.jpg\"><img loading=\"lazy\" class=\"alignright size-full wp-image-10540\" src=\"http:\/\/therapytoronto.ca\/news\/wp-content\/uploads\/2013\/02\/depressed_bullied_worker.jpg\" alt=\"depression\" width=\"200\" height=\"300\" \/><\/a>Chronic inflammation in the bloodstream can &#8216;fan the flames&#8217; of depression<\/strong>, much like throwing gasoline on a fire, according to a new paper from researchers at Rice University and Ohio State University.<\/p>\n<p>&#8216;Inflammation: Depression Fans the Flames and Feasts on the Heat&#8217; appeared in a recent edition of the <em>American Journal of Psychiatry<\/em>. <strong>The study reviewed 200 existing papers on depression and inflammation<\/strong>.<\/p>\n<p>&#8220;In the health area of psychology at Rice, we&#8217;re very focused on the intersection of health behavior, psychology and medicine,&#8221; said Christopher Fagundes, an assistant professor of psychology and co-author of the paper. &#8220;<strong>One thing that we&#8217;re particularly interested in is how stress affects the immune system, which in turn affects diseases and mental health outcomes<\/strong>, the focus of this paper.&#8221;<\/p>\n<p>The authors found that <strong>in addition to being linked to numerous physical health issues, including cancer and diabetes, systemic inflammation is linked to mental health issues such as depression<\/strong>. Among patients suffering from clinical depression, concentrations of two inflammatory markers, CRP and IL-6, were elevated by up to 50 percent.<\/p>\n<p>Fagundes said <strong>chronic inflammation is most common in individuals who have experienced stress in their lives<\/strong>, including lower socio-economic status or those who experienced abuse or neglect as children. Other contributing factors are a high-fat diet and high body mass index.<\/p>\n<p>&#8220;Previous research shows that individuals who have socio-economic issues or had problems in their early lives <strong>are already at higher risk for mental issues because of these stresses in their lives<\/strong>,&#8221; Fagundes said. &#8220;As a result, they often experience a higher occurrence of chronic inflammation, which we have linked to depression.&#8221;<\/p>\n<p>He said that it is normal for humans to have an inflammatory response &#8212; such as redness &#8212; to an area of the body that is injured.<\/p>\n<p>&#8220;This is your immune system working to kill that pathogen, which is a good thing,&#8221; Fagundes said. &#8220;However, <strong>many individuals exhibit persistent systemic inflammation, which we&#8217;re finding is really the root of all physical and mental diseases<\/strong>. Stress, as well as poor diet and bad health behaviors, enhances inflammation.&#8221;<\/p>\n<p>Fagundes noted that a strong support system early in life is critical in helping individuals learn to deal with stress later in life.<\/p>\n<p>The study also found that <strong>depression caused by chronic inflammation is resistant to traditional therapy methods, but can be treated with activities such as yoga, meditation NSAIDS and exercise<\/strong>.<\/p>\n<p>Fagundes hopes the study will shed light on the dangers of bodily inflammation and the steps that can be taken to overcome this health issue.<\/p>\n<p>He is <strong>starting a five-year $3.7 million bereavement study to examine how inflammation impacts depression and disease<\/strong> among those who recently lost a spouse in hopes of finding better ways to treat bereaved older adults.<\/p>\n<p>&#8220;We still have a lot to learn about how inflammation impacts depression, but we are making progress,&#8221; he said &#8220;We hope one day this work will lead to new treatments that are part of standard psychiatric care.&#8221;<\/p><\/blockquote>\n<p>&nbsp;<\/p>\n<!-- AddThis Advanced Settings generic via filter on the_content --><!-- AddThis Share Buttons generic via filter on the_content -->","protected":false},"excerpt":{"rendered":"<p>From the Rice University media release: Chronic inflammation in the bloodstream can &#8216;fan the flames&#8217; of depression, much like throwing gasoline on a fire, according to a new paper from&#8230; <a class=\"read-more-link\" href=\"https:\/\/therapytoronto.ca\/news\/2016\/01\/inflammation-can-fan-the-flames-of-depression\/\">Read more &raquo;<\/a><!-- AddThis Advanced Settings generic via filter on get_the_excerpt --><!-- AddThis Share Buttons generic via filter on get_the_excerpt --><\/p>\n","protected":false},"author":5,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[345,10,351],"tags":[],"_links":{"self":[{"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/posts\/18659"}],"collection":[{"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/comments?post=18659"}],"version-history":[{"count":1,"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/posts\/18659\/revisions"}],"predecessor-version":[{"id":18664,"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/posts\/18659\/revisions\/18664"}],"wp:attachment":[{"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/media?parent=18659"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/categories?post=18659"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/tags?post=18659"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}