{"id":20160,"date":"2017-04-06T09:32:32","date_gmt":"2017-04-06T13:32:32","guid":{"rendered":"http:\/\/therapytoronto.ca\/news\/?p=20160"},"modified":"2017-04-04T18:34:51","modified_gmt":"2017-04-04T22:34:51","slug":"psychiatric-disorders-do-not-increase-risk-of-alzheimers-disease","status":"publish","type":"post","link":"https:\/\/therapytoronto.ca\/news\/2017\/04\/psychiatric-disorders-do-not-increase-risk-of-alzheimers-disease\/","title":{"rendered":"Psychiatric disorders do not increase risk of Alzheimer&#8217;s disease"},"content":{"rendered":"<p>From the University of Eastern Finland press release:<\/p>\n<blockquote><p><img loading=\"lazy\" class=\"alignright size-full wp-image-15342\" src=\"http:\/\/therapytoronto.ca\/news\/wp-content\/uploads\/2013\/08\/schizophrenia-memory-loss.jpg\" alt=\"\" width=\"240\" height=\"218\" \/><strong>Psychiatric disorders do not increase the risk of Alzheimer&#8217;s disease<\/strong>, according to a recent study from the University of Eastern Finland. However, the prevalence of psychiatric diagnoses increased before the Alzheimer&#8217;s diagnosis, which might be due to prodromal symptoms of Alzheimer&#8217;s disease. The results were published in <em>European Psychiatry<\/em>.<\/p>\n<p>History of mood disorder, such as depression, or any psychiatric disorder were associated with a higher risk of Alzheimer&#8217;s disease when psychiatric disorders that occurred at least five years before the Alzheimer&#8217;s diagnosis were taken into account. <strong>However, the associations disappeared when this time window was extended to 10 years<\/strong>. The exponential increase in the prevalence of psychiatric disorders before the diagnosis implies that <strong>some of these psychiatric disorders might actually have been prodromal symptoms of Alzheimer&#8217;s disease<\/strong>. This underlines the importance of <strong>proper differential diagnostics of Alzheimer&#8217;s disease<\/strong>. Further, the findings also highlight the importance of using an appropriate time window when assessing the risk factors of neurodegenerative diseases with a long onset period. Otherwise the identified &#8220;risk factors&#8221; may actually be manifestations of the neurodegenerative disease.<\/p>\n<p>It should also be acknowledged that although psychiatric disorders diagnosed 10-40 years before Alzheimer&#8217;s disease were not related to a higher risk, the life expectancy of persons with psychiatric disorders was, and is still decreased. Thus, those persons with psychiatric disorders who lived long enough to develop Alzheimer&#8217;s disease were a selected sample of all persons with psychiatric disorders.<\/p>\n<p>The study was conducted in the MEDALZ-2005 cohort which included all Finnish community dwellers with clinically verified Alzheimer&#8217;s disease at the end of 2005 and their age, sex and region of residence matched controls (N of case-control pairs 27,948). History of psychiatric disorders since 1972 was extracted from the Finnish Hospital Discharge Register. Chronic disorders and substance abuse were taken into account.<\/p><\/blockquote>\n<!-- AddThis Advanced Settings generic via filter on the_content --><!-- AddThis Share Buttons generic via filter on the_content -->","protected":false},"excerpt":{"rendered":"<p>From the University of Eastern Finland press release: Psychiatric disorders do not increase the risk of Alzheimer&#8217;s disease, according to a recent study from the University of Eastern Finland. However,&#8230; <a class=\"read-more-link\" href=\"https:\/\/therapytoronto.ca\/news\/2017\/04\/psychiatric-disorders-do-not-increase-risk-of-alzheimers-disease\/\">Read more &raquo;<\/a><!-- AddThis Advanced Settings generic via filter on get_the_excerpt --><!-- AddThis Share Buttons generic via filter on get_the_excerpt --><\/p>\n","protected":false},"author":5,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[321,10],"tags":[16,195,194,14,49,158,301,12],"_links":{"self":[{"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/posts\/20160"}],"collection":[{"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/comments?post=20160"}],"version-history":[{"count":2,"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/posts\/20160\/revisions"}],"predecessor-version":[{"id":20172,"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/posts\/20160\/revisions\/20172"}],"wp:attachment":[{"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/media?parent=20160"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/categories?post=20160"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/tags?post=20160"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}