{"id":22586,"date":"2017-08-04T14:36:01","date_gmt":"2017-08-04T18:36:01","guid":{"rendered":"http:\/\/therapytoronto.ca\/news\/?p=22586"},"modified":"2017-08-04T16:37:12","modified_gmt":"2017-08-04T20:37:12","slug":"neural-connections-in-emotional-processing-of-olfactory-stimuli-in-mice","status":"publish","type":"post","link":"https:\/\/therapytoronto.ca\/news\/2017\/08\/neural-connections-in-emotional-processing-of-olfactory-stimuli-in-mice\/","title":{"rendered":"Neural connections in emotional processing of olfactory stimuli in mice"},"content":{"rendered":"<p>From the\u00a0Asociaci\u00f3n RUVID press release:<\/p>\n<blockquote>\n<p id=\"first\" class=\"lead\"><img loading=\"lazy\" class=\"alignright size-medium wp-image-20811\" src=\"http:\/\/therapytoronto.ca\/news\/wp-content\/uploads\/2017\/04\/Mice-300x200.jpg\" alt=\"\" width=\"300\" height=\"200\" \/>The Joint Unit of Functional Neuroanatomy of the universities of Valencia and Jaume I de Castell\u00f3 has described for the first time the <strong>complete map of the neural connections of the anterior cortical nucleus of the amygdala<\/strong>, a key brain region for the <strong>emotional processing of olfactory stimuli<\/strong> of mice. The research has been published in the<em> Journal of Comparative Neurology.<\/em><\/p>\n<div id=\"text\">\n<p>Bernardita C\u00e1diz, Mar\u00eda Abell\u00e1n, Cec\u00edlia Pardo, Ferran Mart\u00ednez and Enrique Lanuza form the research team that has characterized the nervous circuit of the anterior cortical nucleus of the amygdala, partially unknown until now. The work describes the relationship between this nucleus and the other structures from which it receives information, as well as the areas of the brain to which it sends information.<\/p>\n<p>Enrique Lanuza, researcher at the Department of Cell Biology, Functional Biology and Physical Anthropology at the University of Val\u00e8ncia, emphasizes that olfactory information has an intrinsic emotional value. &#8220;This work shows that this information reaches directly into the anterior cortical nucleus of the amygdala, which is directly interconnected with areas that process pheromonal information (which plays a key role in rodents&#8217; sexual behaviour) and also with nuclei related to defensive and aggressive behaviour,&#8221; says the expert.<\/p>\n<p>In addition, the member of the Joint Unit of Functional Neuroanatomy points out that this olfactory nucleus of the amygdala is connected with regions that have been shown to be involved in Pavlovian learning, that is, to associate a neutral stimulus with a reward or a negative experience.<\/p>\n<p>&#8220;Although experiments have been performed on mice, <strong>these areas of the brain are evolutionarily highly conserved, and it is therefore reasonable to expect an important similarity with the human brain<\/strong>,&#8221; explains Lanuza. In addition, &#8220;<strong>smells are particularly evocative stimuli<\/strong>, and often very pleasant or unpleasant, so that we avoid being in places where it smells bad. Thus, to smell good is a good social letter of presentation,&#8221; says the lecturer of the Faculty of Biological Sciences of the University of Val\u00e8ncia.<\/p>\n<p>The experiment was carried out with 15 female mice Mus musculus, the species of this most common rodent. The team has performed intracerebral injection of tracers (inert molecules), detectable by the emission of fluorescent light or by their chemical characteristics. In this way, thanks to the tracing of these molecules, the research team has observed the connections of this key structure in the processing of the emotional value of odours.<\/p>\n<\/div>\n<\/blockquote>\n<!-- AddThis Advanced Settings generic via filter on the_content --><!-- AddThis Share Buttons generic via filter on the_content -->","protected":false},"excerpt":{"rendered":"<p>From the\u00a0Asociaci\u00f3n RUVID press release: The Joint Unit of Functional Neuroanatomy of the universities of Valencia and Jaume I de Castell\u00f3 has described for the first time the complete map&#8230; <a class=\"read-more-link\" href=\"https:\/\/therapytoronto.ca\/news\/2017\/08\/neural-connections-in-emotional-processing-of-olfactory-stimuli-in-mice\/\">Read more &raquo;<\/a><!-- AddThis Advanced Settings generic via filter on get_the_excerpt --><!-- AddThis Share Buttons generic via filter on get_the_excerpt --><\/p>\n","protected":false},"author":5,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[5,6,324],"tags":[42,122,93,436,94],"_links":{"self":[{"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/posts\/22586"}],"collection":[{"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/comments?post=22586"}],"version-history":[{"count":2,"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/posts\/22586\/revisions"}],"predecessor-version":[{"id":22706,"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/posts\/22586\/revisions\/22706"}],"wp:attachment":[{"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/media?parent=22586"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/categories?post=22586"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/tags?post=22586"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}