“Green tea is the second most consumed beverage in the world after water, and is grown in at least 30 countries,” said Xuebo Liu, Ph.D., a researcher at the College of Food Science and Engineering, Northwest A&F University, in Yangling, China. “The ancient habit of drinking green tea may be a more acceptable alternative to medicine when it comes to combatting obesity, insulin resistance, and memory impairment.”<\/p>\n Liu and colleagues divided 3-month-old male C57BL\/6J mice into three groups based on diet:<\/p>\n 1) a control group fed with a standard diet,<\/p>\n 2) a group fed with an HFFD diet, and 3) a group fed with an HFFD diet and 2 grams of EGCG per liter of drinking water.<\/p>\n For 16 weeks, researchers monitored the mice and found that those fed with HFFD had a higher final body weight than the control mice, and a significantly higher final body weight than the HFFD+EGCG mice. In performing a Morris water maze test, researchers found that mice in the HFFD group took longer to find the platform compared to mice in the control group. The HFFD+EGCG group had a significantly lower escape latency and escape distance than the HFFD group on each test day. When the hidden platform was removed to perform a probe trial, HFFD-treated mice spent less time in the target quadrant when compared with control mice, with fewer platform crossings. The HFFD+EGCG group exhibited a significant increase in the average time spent in the target quadrant and had greater numbers of platform crossings, showing that EGCG could improve HFFD-induced memory impairment.<\/p>\n “Many reports, anecdotal and to some extent research-based, are now greatly strengthened by this more penetrating study,” said Thoru Pederson, Ph.D., Editor-in-Chief of\u00a0The FASEB Journal<\/em>.<\/p>\n<\/div>\n<\/blockquote>\n","protected":false},"excerpt":{"rendered":" From the\u00a0Federation of American Societies for Experimental Biology press release: A study published online in\u00a0The FASEB Journal, involving mice, suggests that EGCG (epigallocatechin-3-gallate), the most abundant catechin and biologically active… Read more »<\/a><\/p>\n","protected":false},"author":5,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[336],"tags":[42,18,208,299,93,207],"_links":{"self":[{"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/posts\/22830"}],"collection":[{"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/comments?post=22830"}],"version-history":[{"count":2,"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/posts\/22830\/revisions"}],"predecessor-version":[{"id":22953,"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/posts\/22830\/revisions\/22953"}],"wp:attachment":[{"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/media?parent=22830"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/categories?post=22830"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/tags?post=22830"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}![\"\"](\"http:\/\/therapytoronto.ca\/news\/wp-content\/uploads\/2013\/02\/green-tea-canstockphoto8859620.jpg\")
A study published online in\u00a0The FASEB Journal<\/em>, involving mice, suggests that EGCG (epigallocatechin-3-gallate)<\/strong>, the most abundant catechin and biologically active component in green tea, could alleviate high-fat and high-fructose (HFFD)-induced insulin resistance and cognitive impairment<\/strong>. Previous research pointed to the potential of EGCG to treat a variety of human diseases, yet until now, EGCG’s impact on insulin resistance and cognitive deficits triggered in the brain by a Western diet remained unclear.<\/p>\n