{"id":23849,"date":"2017-10-04T10:27:28","date_gmt":"2017-10-04T14:27:28","guid":{"rendered":"http:\/\/therapytoronto.ca\/news\/?p=23849"},"modified":"2017-09-29T16:58:18","modified_gmt":"2017-09-29T20:58:18","slug":"study-suggests-even-open-label-placebos-work-if-they-are-explained","status":"publish","type":"post","link":"https:\/\/therapytoronto.ca\/news\/2017\/10\/study-suggests-even-open-label-placebos-work-if-they-are-explained\/","title":{"rendered":"Study suggests even open-label placebos work, if they are explained"},"content":{"rendered":"<p>From the\u00a0Universit\u00e4t Basel press release:<\/p>\n<blockquote>\n<p id=\"first\" class=\"lead\"><img loading=\"lazy\" class=\"alignright size-full wp-image-15981\" src=\"http:\/\/therapytoronto.ca\/news\/wp-content\/uploads\/2013\/12\/magnesium-pills.jpg\" alt=\"\" width=\"290\" height=\"185\" \/><strong>For some medical complaints, open-label placebos work just as well as deceptive ones<\/strong>. As psychologists from the University of Basel and Harvard Medical School report in the journal\u00a0<em>Pain<\/em>, <strong>the accompanying rationale plays an important role when administering a placebo<\/strong>.<\/p>\n<div id=\"text\">\n<p>The successful treatment of certain physical and psychological complaints can be explained to a significant extent by the placebo effect. The crucial question in this matter is <strong>how<\/strong> <strong>this effect can be harnessed without deceiving the patients<\/strong>. Recent empirical studies have shown that <strong>placebos administered openly have clinically significant effects on physical complaints such as chronic back pain, irritable bowel syndrome, episodic migraine and rhinitis<\/strong>.<\/p>\n<p><strong>Cream for pain relief<\/strong><\/p>\n<p>For the first time, researchers from the University of Basel, along with colleagues from Harvard Medical School, have compared the effects of administering open-label and deceptive placebos. The team conducted an experimental study with 160 healthy volunteers who were exposed to increasing heat on their forearm via a heating plate. The participants were asked to manually stop the temperature rise as soon as they could no longer stand the heat. After that, they were given a cream to relieve the pain.<\/p>\n<p>Some of the participants were deceived during the experiment: they were told that they were given a pain relief cream with the active ingredient lidocaine, although it was actually a placebo. Other participants received a cream that was clearly labeled as a placebo; they were also given fifteen minutes of explanations about the placebo effect, its occurrence and its effect mechanisms. A third group received an open-label placebo without any further explanation.<\/p>\n<p>The subjects of the first two groups reported a significant decrease in pain intensity and unpleasantness after the experiment. &#8220;The previous assumption that placebos only work when they are administered by deception needs to be reconsidered,&#8221; says Dr. Cosima Locher, a member of the University of Basel&#8217;s Faculty of Psychology and first author of the study.<\/p>\n<p><strong>Stronger pain when no rationale is given<\/strong><\/p>\n<p>When detailed explanations of the placebo effect were absent &#8212; as in the third group &#8212; the subjects reported significantly more intense and unpleasant pain. This suggests the crucial role of the <strong>accompanying rationale and communication<\/strong> when administering a placebo; the researchers speak of a <strong>narrative<\/strong>. The ethically problematic aspect of placebos, the deception, thus does not appear all that different from a transparent and convincing narrative. &#8220;Openly administering a placebo offers new possibilities for using the placebo effect in an ethically justifiable way,&#8221; says co-author Professor Jens Gaab, Head of the Division of Clinical Psychology and Psychotherapy at the University of Basel.<\/p>\n<\/div>\n<\/blockquote>\n<!-- AddThis Advanced Settings generic via filter on the_content --><!-- AddThis Share Buttons generic via filter on the_content -->","protected":false},"excerpt":{"rendered":"<p>From the\u00a0Universit\u00e4t Basel press release: For some medical complaints, open-label placebos work just as well as deceptive ones. As psychologists from the University of Basel and Harvard Medical School report&#8230; <a class=\"read-more-link\" href=\"https:\/\/therapytoronto.ca\/news\/2017\/10\/study-suggests-even-open-label-placebos-work-if-they-are-explained\/\">Read more &raquo;<\/a><!-- AddThis Advanced Settings generic via filter on get_the_excerpt --><!-- AddThis Share Buttons generic via filter on get_the_excerpt --><\/p>\n","protected":false},"author":5,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[526,60],"tags":[75,190,363,341,12],"_links":{"self":[{"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/posts\/23849"}],"collection":[{"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/comments?post=23849"}],"version-history":[{"count":2,"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/posts\/23849\/revisions"}],"predecessor-version":[{"id":23886,"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/posts\/23849\/revisions\/23886"}],"wp:attachment":[{"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/media?parent=23849"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/categories?post=23849"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/therapytoronto.ca\/news\/wp-json\/wp\/v2\/tags?post=23849"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}